Komen Scholar: Charles M. Perou, Ph.D.

Charles M. Perou, Ph.D., is the May Goldman Shaw Distinguished Professor of Molecular Oncology, Co-Director of the Lineberger Comprehensive Cancer Center (LCCC) Bioinformatics Group, Program Co-Director of the LCCC Breast Cancer Research Program, Professor in the Department of Genetics, and Pathology & Laboratory Medicine, University of North Carolina. Dr. Perou’s research has focused on genomics to identify breast cancer subtypes that are of prognostic and predictive value. Dr. Perou aims at translating his findings to the clinic, by using genomics to inform therapeutic decision making. With Komen funding and in sponsorship with the Danaher Corporation, his research started showing how the immune system contributes to patient outcomes and how immunotherapies had potential in treating aggressive breast cancers, like triple negative and basal-like breast cancers. With additional Komen funding, Dr. Perou aims at harnessing big data to molecularly characterize HER2+ breast cancer and identify additional genetic drivers that could be targeted to improve patient outcomes. Dr. Perou was the first to deliver the Komen-funded AACR Distinguished Lecture on the Science of Cancer Health Disparities in 2010. He received the Brinker Award for Scientific Distinction in Basic Science in 2016.